Advice columnist Dan Burns (Carell) has his hands full with three daughters that he's not willing to let grow up. The girls still grieve for their mother who died four years ago, and Dan hasn't made any attempts to date. So he's pleasantly surprised when he meets Marie (Juliette Binoche) at a bookstore when he goes to his parents' Rhode Island home for the annual family reunion. But his joy is short-lived when he discovers that she is dating his brother (Dane Cook), forcing Dan to hide his feelings and chemistry with Marie.