While on a promotional tour for a corrupt international conglomerate, a mercenary TV actor Ricky Coogin travels to Santa Flan, a South American country. With his best friend, and his would-be girlfriend along for the trip, they are unwillingly transformed into circus freaks by sleazy road-show proprietor Elijah C. Skuggs. Ricky, now a beast-boy, and his cohorts soon join the ranks of Sockhead, Rosie the Pinhead, and the Hideous Frogman, to hatch a scheme to steal Skuggs' gene-altering formula, thereby returning everyone to their original states. Look out for an uncredited cameo from Keanu Reeves as Dog Boy.