Spider-Man 3 rumours begin
The third Spidey film will see the cast and crew come back together next year, with the film set for a May 2007 release.
And director Sam Raimi and producer Avi Arad have hinted about what is to come.
Concerning specific plot details Arad declared: "It's way too early to tell you."
But Raimi did drop a few hints.
Keen-eyed comic fans might well have noticed a couple of future villains dotted around the second film.
One-armed scientist Dr Curt Connors (who goes on to become The Lizard) was there, John Jameson goes on to turn into Man-Wolf (but other Spider-fans think he may become Venom - the evil version of our hero).
When asked by Empire magazine about these options, Raimi frustratingly commented: "All those are possibilities and I am thinking about that."
But there is a much more obvious villain as well.
At the end of the film Harry Osborn finds his father's secret Goblin lair. . .
"But who knows if Harry Osborn will actually pick up that green sauce and realise... 'you know, I understand why Spider-Man killed my father, [because] he was a murderer. I can now let my anger float away'. Or does he think 'I now have the means to vanquish my foe. Lemme at him!'."
Titles related to this article